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本文用改进的M(?)erller法显示酸性α醋酸萘酯酶(ANAE)以观察慢性萎缩性胃炎(B型为主)和胃癌患者外周血中T淋巴细胞数,作者并根据ANAE染色颗粒的数字和大小,以积分法代表ANAE活性。观察表明,胃癌和萎缩性胃炎患者的T淋巴细胞水平(即ANAE阳性率,以上各为46.2±1.87％及54.4±1.48％)明显低于正常对照者(72.7±5.9％),而萎缩性胃炎患者的T细胞水平明显高于胃癌患者,三者间既有差别而又密切相关;以上提示细胞免疫功能的改变可能在B型萎缩性胃炎的发生和发展中起一定的作用。
In this paper, the improved M(?)erller method was used to show acid alpha-naphthylacetatease (ANAE) to observe the number of T lymphocytes in peripheral blood of patients with chronic atrophic gastritis (type B predominant) and gastric cancer. Numbers and sizes represent the ANAE activity by the integral method. Observations showed that T-lymphocyte levels in patients with gastric cancer and atrophic gastritis (ie, the positive rate of ANAE, 46.2±1.87% and 54.4±1.48% respectively) were significantly lower than those in normal controls (72.7±5.9%), and atrophic gastritis The patient’s T-cell level was significantly higher than that of gastric cancer patients. There were differences between the three patients and they were closely related. The above suggested that changes in cellular immune function may play a role in the occurrence and development of type B atrophic gastritis.