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目的评价3种头孢菌素类抗生素治疗下呼吸道感染的成本与效果。方法将126例下呼吸道感染患者随机分成A、B、C3组。A组给予头孢呋辛钠1.5 g,iv gtt,tid;B组给予头孢曲松钠2.0 g,iv gtt,qd;C组给予头孢哌酮钠2.0 g,iv gtt,bid;疗程均为7 d。观察3组的临床疗效,并进行成本-效果分析。结果 A、B、C3组的有效率分别为83.33%、84.09%和82.50%,差异无统计学意义(P>0.05);3组的治疗成本分别为760.20圆、701.40圆和1128.40圆;成本-效果比分别为9.12、8.34和13.68。结论头孢曲松钠(2.0 g,iv gtt,qd)是治疗下呼吸道感染的较佳方案。
Objective To evaluate the cost and effectiveness of three cephalosporin antibiotics in the treatment of lower respiratory tract infections. Methods 126 cases of lower respiratory tract infection were randomly divided into A, B, C3 group. Group A was given cefuroxime sodium 1.5 g, iv gtt, tid; Group B was given ceftriaxone sodium 2.0 g, iv gtt, qd; Group C was given cefoperazone sodium 2.0 g, iv gtt, bid; The clinical efficacy of the three groups was observed and cost-effectiveness analysis was performed. Results The effective rates of group A, B and C3 were 83.33%, 84.09% and 82.50% respectively, with no significant difference (P> 0.05). The cost of treatment in group A was 760.20, 701.40 and 1128.40 respectively. The cost- The results were 9.12, 8.34 and 13.68 respectively. Conclusion Ceftriaxone sodium (2.0 g, iv gtt, qd) is the best treatment for lower respiratory tract infection.