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目的探讨无创呼吸机对老年急性期慢性阻塞性肺疾病合并呼吸衰竭的临床应用效果。方法 90例老年急性期慢性阻塞性肺疾病合并呼吸衰竭患者,随机分为对照组和研究组,各45例。对照组接受临床常规治疗,研究组在常规治疗基础上加用无创呼吸机,记录两组动脉血二氧化碳分压(PaCO_2)、pH、动脉血氧分压(PaO_2)等血气分析指标治疗前后变化情况。结果两组治疗前血气分析指标比较,差异无统计学意义(P>0.05)。治疗后研究组pH(7.38±0.04)、PaCO_2(49.47±9.35)mmHg(1 mmHg=0.133 kPa)、PaO_2(79.54±9.81)mmHg;对照组pH(7.31±0.05)、PaCO_2(63.75±13.42)mm Hg、PaO_2(62.92±7.88)mmHg,治疗后研究组血气分析指标改善效果优于对照组,差异有统计学意义(P<0.05)。结论对老年急性期慢性阻塞性肺疾病合并呼吸衰竭患者给予常规治疗基础上加用无创呼吸机可获得更为理想的临床疗效,最大限度地保障了患者呼吸畅通性,改善患者心、肺功能,有利于降低死亡率,保证患者生命安全,值得临床推广。
Objective To investigate the clinical effect of noninvasive ventilator on elderly patients with chronic obstructive pulmonary disease and respiratory failure. Methods Ninety elderly patients with chronic obstructive pulmonary disease and respiratory failure were randomly divided into control group and study group, with 45 cases in each group. The control group received routine clinical treatment. The study group was given noninvasive ventilator on the basis of routine treatment. The changes of blood gas analysis indexes such as PaCO 2, pH and PaO 2 of arterial blood were recorded before and after treatment . Results There was no significant difference between the two groups in blood gas analysis before treatment (P> 0.05). After treatment, the mean arterial blood pressure of the control group was (7.38 ± 0.04), PaCO_2 (49.47 ± 9.35) mmHg (1 mmHg = 0.133 kPa) and PaO_2 (79.54 ± 9.81) Hg, PaO_2 (62.92 ± 7.88) mmHg. After treatment, the improvement effect of blood gas analysis index in the study group was better than that in the control group, the difference was statistically significant (P <0.05). Conclusion In the elderly patients with chronic obstructive pulmonary disease and respiratory failure combined with conventional treatment based on the use of noninvasive ventilator to obtain more ideal clinical efficacy, to maximize the protection of the patient’s breathing and improve the patient’s heart and lung function, Help to reduce the mortality rate and ensure the patient’s life safety, worthy of clinical promotion.