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本文用小鼠骨髓细胞微核试验、睾丸生殖细胞染色体畸变试验和精子畸形试验,对含2.5%八氯二丙醚(S2)的无烟蚊香进行了致突变性检测。发现染毒浓度为1346~5382mg/m~3时对骨髓细胞和睾丸染色体;浓度为6370~26910mg/m~3时对精子畸形率均无明显影响。提示在本实验条件下未见含S2无烟蚊香烟雾有明显的致突变性。
In this study, the mutagenicity of smokeless mosquito coils containing 2.5% octachlorodipropyl ether (S2) was tested using the micronucleus test of mouse bone marrow cells, chromosomal aberration test of testis germ cells and sperm abnormality test. It was found that the concentration of 1346 ~ 5382mg / m ~ 3 on bone marrow cells and testicular chromosomes; concentration of 6370 ~ 26910mg / m ~ 3 sperm deformity rate had no significant effect. Suggest that in this experimental conditions, no smoke containing S2 smoke-free mosquito obvious mutagenicity.