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目的 观察帕米膦酸二钠 (APD)治疗恶性肿瘤骨转移疼痛的疗效。方法 4 1例患者均应用APD治疗 ,第 1天给予APD 6 0mg加入 5 %葡萄糖注射液 5 0 0ml中静滴 ,4小时滴完 ,第 2天给予APD 30mg加入 5 %葡萄糖注射液 5 0 0ml中静滴 ,4小时滴完 ,30天重复 1次。结果 治疗后止痛总有效率 (CR +PR)为 80 4 %。结论 APD对恶性肿瘤溶骨性骨转移引起的疼痛有较好的疗效 ,对合并化疗的病人效果更好 ,不良反应轻微 ,病人可以耐受
Objective To observe the curative effect of pamidronate disodium (APD) on bone metastasis of malignant tumor. Methods 4 patients were treated with APD, the first day of APD 60mg added 5% glucose injection 500ml intravenous drip finished 4 hours, on the second day APD 30mg added 5% glucose injection 500ml In the intravenous drip, drip finished 4 hours, 30 days to repeat 1 times. Results After treatment, the total effective rate of pain relief (CR + PR) was 80 4%. Conclusions APD is effective in treating pain caused by osteolytic bone metastases of malignant tumors and has better effect on patients with combined chemotherapy, with mild side effects and patients tolerated