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1980年16844人中普查出的144例T2DM及24例IGT者予生活方式及药物干预,25年后对此人群进行跟踪。结果:T2DM先后服用降糖药治疗者>17.6%;应用胰岛素或与口服降血糖药联用或先后阶段性应用大约占79.4%;仅以饮食和体育锻炼治疗者2.9%。4例T2DM患者逆转为IGT。病死率为70.2%(80/114),死因为心脑血管病、多脏器功能衰竭、慢性肾功能不全、恶性肿瘤等。IGT者失访2例,13.6%发展成DM,40.9%仍为IGT,45.5%转为NGT。结论:DM是可防的,应做到早发现、综合干预、强化治疗。
Of the 16844 people surveyed in 1980, 144 T2DM patients and 24 IGT patients were given life-style and drug interventions. The population was followed up 25 years later. Results: T2DM treated patients with hypoglycemic agents were> 17.6%; insulin or oral hypoglycemic agents used in combination or sequential application accounted for about 79.4%; diet and physical exercise only 2.9%. 4 cases of T2DM patients reversed to IGT. Case fatality rate was 70.2% (80/114), death due to cardiovascular and cerebrovascular disease, multiple organ failure, chronic renal insufficiency, malignant tumors. Two patients lost IGT, 13.6% developed DM, 40.9% remained IGT and 45.5% changed to NGT. Conclusion: DM is preventable, should be detected early, comprehensive intervention, intensive treatment.