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目的:对3种梅毒检测方法进行比较分析,选择适合临床筛查的方法。方法:50例非梅毒患者为对照组,临床诊断梅毒患者64例为实验组,分别进行酶联免疫吸附试验(ELISA)、快速血浆反应素试验(RPR)和梅毒螺旋体颗粒凝集试验(TPPA)三种试验方法的检测,比较检测结果。结果:ELISA法对照组阴性49例(特异性98.0%),实验组阳性63例(灵敏度98.4%);RPR法阴性46例(特异性92.0%),实验组阳性24例(灵敏度37.5%);TPPA法对照组阴性50例(特异性100.0%),实验组阳性60例(灵敏度96.9%)。结论:ELISA法有很好的灵敏度和特异性,是进行梅毒检测的首选方法。
Objective: To compare and analyze the three methods of detecting syphilis and choose the method suitable for clinical screening. Methods: Totally 50 non-syphilis patients were selected as the control group. Sixty-four patients with syphilis were enrolled in the experiment. Enzyme-linked immunosorbent assay (ELISA), Rapid plasma reactive element assay (RPR) and Treponema pallidum Particle Agglutination Test Test method of test, compare the test results. Results: In the control group, 49 cases were negative (specificity 98.0%), 63 cases were positive (sensitivity 98.4%), 46 cases were negative with RPR (92.0% specificity), 24 cases were positive (sensitivity 37.5%). TPPA law negative group of 50 cases (100.0% specificity), the experimental group was 60 cases (96.9% sensitivity). Conclusion: ELISA has good sensitivity and specificity, which is the first choice for the detection of syphilis.