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干扰素对于病毒性肝炎仍为首选药物,但不是最理想的药物,据笔者分析这与给药途径有关。因为按传统的方法通过肌肉注射给药后,干扰素的脏器浓度为局部>肾>脾>肺>生殖系>肝>心>脑>脂肪,肝脏的干扰素浓度仅为第六位,如改变给药途径,或许能提高肝脏内的药物浓度,进而提高其疗效。笔者曾以肝内直接注射安福隆(干扰素α-2b)的方式给药,自1997年4月～1998年7月搜集资料完整的病例共100例,兹小结于后供参考。
Interferon for viral hepatitis is still the drug of choice, but not the most ideal drug, according to my analysis of this and the route of administration. Because according to the traditional method of intramuscular administration, the concentration of interferon in the organs of local> kidney> spleen> lung> germ> liver> heart> brain> fat, liver interferon concentration only sixth, such as Change the route of administration, may increase the concentration of drugs in the liver, and thus improve its efficacy. The author had intrahepatic direct injection of An Fulong (interferon alpha-2b) way of administration, from April 1997 to July 1998 a total of 100 cases of complete data collection, the following summary for reference.