二十世纪八、九十年代疼痛的系统综述中有一篇关于鞘内和硬膜外输注阿片类药物的综述揭示,脊髓途径镇痛已确立为治疗急、慢性及癌性疼痛的主要方式。而今经脊髓途径镇痛正越来越多地用于非住院患者慢性和癌性疼痛的长期治疗。最初于脊髓用阿片类药物作选择性阻滞疼痛的构想,随着技术的改进,尤其是阿片类和非 A review of intrathecal and epidural opioid administration in a systematic review of pain in the 1980s and 1990s revealed that spinal route analgesia has been established as the primary treatment for acute, chronic, and cancerous pain. Today, spinal route analgesia is increasingly being used for long-term treatment of chronic and cancerous pain in non-hospitalized patients. The concept of opioid blocking of pain initially in the spinal cord, with technical improvements, especially opiates and non