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近7～8年来某些病毒证明与胃肠炎有关,如腺病毒,星状病毒,嵌杯样病毒,冠状病毒,Norwalk样病毒与轮状病毒。婴幼儿的急性胃肠炎常和轮状病毒有关,青年与成人之病因尚不明确,Norwalk样病毒可能是主要病因之一。引起胃肠炎的病毒,在实验室细胞培养中不能繁殖,而电镜为检查之主要方法。免疫电镜检查可测定感染时特异抗体之增加,又能区别形态相似病毒的不同抗原。此类方法较为敏感,有助于发展胃肠炎病毒之细胞培养,并将大大促进流行病学的研究与疫苗的制备。
Some viruses have been proved to be associated with gastroenteritis in the past seven to eight years, such as adenovirus, astrovirus, caecum-like virus, coronavirus, Norwalk-like virus and rotavirus. Acute gastroenteritis in infants and young children is often associated with rotavirus. The etiopathogenisis of young adults and adults are not clear. Norwalk-like virus may be one of the major causes. Gastroenteritis virus, laboratory cell culture can not reproduce, and electron microscopy as the main method of inspection. Immunoelectron microscopy can detect the increase of specific antibodies during infection, and can distinguish different antigens of morphologically similar viruses. Such methods are more sensitive to the development of cell cultures of gastroenteritis virus and will greatly facilitate epidemiological studies and vaccine preparation.