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目的评价莫沙比利联合胃肠起搏治疗糖尿病胃轻瘫(DGP)的疗效。方法将60例糖尿病胃轻瘫患者随机分为两组,治疗组采用莫沙比利联合胃肠起搏治疗,对照组单用莫沙比利治疗,疗程均为2周。治疗前后进行消化道症状评分。结果治疗组消化道症状积分下降显著高于对照组。治疗组总有效率90.0%,对照总有效率63.3%,两组比较差异有统计学意义(P<0.05)。结论使用莫沙比利联合胃肠起搏治疗能有效缓解糖尿病胃轻瘫(DGP)的症状。
Objective To evaluate the efficacy of mosapride and gastrointestinal pacing in the treatment of diabetic gastroparesis (DGP). Methods Sixty diabetic patients with gastroparesis were randomly divided into two groups. The treatment group was treated with mosapride and gastrointestinal pacing. The control group was treated with mosapride alone for 2 weeks. Before and after treatment of gastrointestinal symptoms scores. Results The scores of digestive symptoms in treatment group were significantly lower than those in control group. The total effective rate was 90.0% in the treatment group and 63.3% in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion Mosapride combined with gastrointestinal pacing can effectively relieve the symptoms of diabetic gastroparesis (DGP).