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1993年Bazzoli报告了一种新的、小剂量、短程三联疗法治愈HP感染,本研究目的是进一步证实这种疗法的有效性及耐受性。 方法:116例经临床检查及活检证实有HP感染,其中女34例,男82例,年龄19～85岁,平均52岁,其中活动性十二指肠溃疡35例,活动性胃溃疡6例,已愈合的十二指肠溃疡47例,溃疡样消化不良28例。剔除服用非类固醇抗炎药者。快速尿素酶试验确定HP情况。所有病人都按Bazzoli的一周三联疗法服用奥美拉唑20mg每日二次,克拉霉素250mg每
In 1993 Bazzoli reported a new, low-dose, short-course triple therapy for HP infection. The purpose of this study was to further confirm the efficacy and tolerability of this regimen. Methods: One hundred and sixteen cases of HP infection were confirmed by clinical examination and biopsy. Among them, 34 were female and 82 were male, ranging in age from 19 to 85 years (mean 52 years). Among them, 35 had active duodenal ulcer, 6 had active gastric ulcer , Healed duodenal ulcer in 47 cases, ulcer-like dyspepsia in 28 cases. Remove non-steroidal anti-inflammatory drugs. Rapid urease test to determine the HP situation. All patients according to Bazzoli week triple therapy omeprazole 20mg twice daily, clarithromycin 250mg