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目的：比较Ｓｔ．Ｔｈｏｍａｓ心脏停搏液对成年和幼年兔心肌缺血—再灌注损伤的保护效果。方法：雄性成年和幼年白兔离体心脏，用Ｌａｎｇｅｎｄｏｒｆ装置灌流，预灌后行缺血—再灌注试验，于缺血期间施加Ｓｔ．Ｔｈｏｍａｓ停搏液，观察心肌功能和超微结构的变化。结果：在冠状动脉流量、心肌收缩幅度和静息张力的恢复百分率以及超微结构方面，Ｓｔ．Ｔｈｏｍａｓ停搏液对成年兔心肌均有良好的保护作用，但对幼年兔心肌的保护效果不显著。结论：初步证实Ｓｔ．Ｔｈｏｍａｓ停搏液对幼年兔心肌缺血—再灌注损伤的保护效果比成年兔差。
Purpose: Compare St. Protection of Thomas Cardioplegic Solution on Myocardial Ischemia - Reperfusion Injury in Adult and Juvenile. Methods: Male and adult white rabbits were isolated from the heart, perfused with Langendorf apparatus, pre-filled with ischemia-reperfusion test and St. Thomas cardioplegia to observe changes in myocardial function and ultrastructure. Results: In terms of coronary flow, percentage of myocardial contractile amplitude and resting recovery, and ultrastructure, St. Thomas cardioplegia has a good protective effect on adult rabbit myocardium, but its effect on myocardial protection in young rabbits is not significant. Conclusion: Preliminary confirmation of St. Thomas cardioplegia protective effect on myocardial ischemia-reperfusion injury in young rabbits than adult rabbits.