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长链非编码RNA是人体基因中不具备蛋白编码功能的核酸序列。随着人体基因工程科研项目的开展,长链非编码RNA逐渐被证实并非转录噪音,其所具有的多种生物学功能在很大程度上影响人类健康。既往有研究证实,长链非编码RNA表达异常与肿瘤疾病相关,该文将以次为基础,针对食管鳞癌总结近期在这一领域内长链非编码RNA的研究进展并对其临床意义进行分析和探讨,旨在为鳞癌的分子诊断与治疗提供参考。
Long-chain non-coding RNA is a human gene does not have the function of protein coding nucleic acid sequence. With the development of human genetic engineering research projects, long-chain non-coding RNA has gradually been proved not to be transcriptional noise, and its various biological functions greatly affect human health. Previous studies have confirmed that abnormal expression of long-chain non-coding RNA is associated with oncological diseases. This article will summarize the recent progress in the research of long-chain non-coding RNA in this area and its clinical significance for esophageal squamous cell carcinoma Analysis and discussion, aims to provide a reference for molecular diagnosis and treatment of squamous cell carcinoma.