食管癌上皮细胞于体外经血卟啉与光照处理后,发现空细胞增多,线粒体退变,空泡形成,常染色质退变。细胞间隙变大,微绒毛减少,细胞膜系统出现破坏性改变,使细胞停于有丝分裂中期。可见桥粒,张力原纤维,高尔基复合器增多,表明癌细胞在受累的同时,出现某些细胞修复的改变。 After esophageal epithelial cells were treated with hematoporphyrin and light in vitro, they found that the number of empty cells increased, mitochondria degenerated, vacuoles formed, and declining chromatin. The cell gap becomes larger, the microvilli decrease, and the cell membrane system undergoes a destructive change that stops cells in the middle of mitosis. Visible desmosomes, tension fibrils, and Golgi apparatus increased, suggesting that while cancer cells are undergoing, some cell repair changes have occurred.