论文部分内容阅读
目的探索早产、低出生体重儿神经心理行为发育,以早期干预,改善预后。方法以西安市莲湖区和碑林区14所社区卫生服务中心为项目点,调查项目点内2011年10月1日-2013年9月30出生的所有常住早产儿、低出生体重儿共303人。根据知情同意将144名早产、低出生体重儿(144/303)设为研究组、随机选取52名同期出生、同社区居住的正常足月儿为对照组,比较两组脑瘫、运动发育落后、孤独症谱系障碍的发生率,对比两组婴幼儿智力发育水平。结果研究组144例GESLL测评(GESLL)异常54例,孤独症谱系障碍筛查阳性10例,脑瘫(痉挛型)2例,运动发育落后11例。对照组52例GESLL测评异常3例,1例诊断为运动发育落后,无脑瘫及孤独症谱系障碍病例。两组GESELL各能区分值比较:研究组各能区分值明显低于对照组,差异有统计学意义(P<0.05)。结论早产、低出生体重儿有高风险出现神经心理行为发育障碍,加强发育早期的监测对预防神经心理行为发育障碍具有重要意义。
Objective To explore the neuropsychological and behavioral development of premature and low birth weight infants with early intervention and improve prognosis. Methods A total of 303 preterm infants and low birth weight infants born from October 1, 2011 to September 30, 30 in Lianhu District of Beilian City and 14 community health service centers in Beilin District were investigated. According to the informed consent, 144 preterm and low birth weight infants (144/303) were enrolled in the study group. Fifty-two normal full-term children born in the same community and living in the same community were selected as the control group. Cerebral palsy, The incidence of autism spectrum disorders, compared with the level of mental development of infants and young children in two groups. Results In the study group, 144 patients with abnormal GESLL (54 cases), 10 cases with autism spectrum disorder screening (positive), 2 cases with cerebral palsy (spastic) and 11 cases with backward movement. In the control group, 52 cases were abnormal in GESLL, 3 cases were diagnosed as abnormal, and 1 case was diagnosed as out-of-motion. There were no cases of cerebral palsy and autism spectrum disorder. The difference between the two groups of GESELL can distinguish: the research group can distinguish value was significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusions There is a high risk of neuropsychological and behavioral dysplasia in preterm and low birth weight infants. It is of great importance to strengthen early monitoring to prevent neuropsychological and behavioral disorders.