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癌基因c-sis是PDGF-Ⅱ链(Platelet-Derived Growth Factor,PDGF)的编码基因。PDGF可以诱导细胞c-myc和c-fos等癌基因的表达,而c-myc和c-fos癌基因与肝癌形成有密切关系。
The oncogene c-sis is a gene encoding PDGF-II chain (PDG). PDGF can induce the expression of oncogenes such as c-myc and c-fos, while c-myc and c-fos oncogenes are closely related to the formation of hepatocellular carcinoma.