论文部分内容阅读
目的 研究吸烟对骨密度的影响。方法 采用现况研究法 ,对 386例 (吸烟者 15 7例、非吸烟者 2 2 9例 )中国北方汉族男性人群进行骨密度测量和问卷调查 ,逐步回归方法分析主要影响因素 ,用方差分析和协方差分析法了解吸烟对骨密度的影响。结果 各部位骨密度值随吸烟量的增加及吸烟年限的延长而下降。日吸烟量超过 15支者 ,腰椎、股骨颈、Ward三角区和全身骨密度值为1 12 7、0 95 2、0 844和 1 148g/cm2 ,均显著低于日吸烟量未超过 15支者 (1 179、1 0 0 2、0 90 7和 1 2 19g/cm2 ) ,其中股骨颈和Ward三角区骨密度也分别显著低于非吸烟者 (0 998和 0 896g/cm2 ) ;修正体重等混杂因素后 ,这种差异在腰椎和全身部位仍然显著。同时吸烟 15年以上者 ,其骨密度值比日吸烟量少于 15支且吸烟不足 15年者低 4 6 %～ 6 7%。结论 研究初步显示吸烟者骨密度较低
Objective To study the effect of smoking on bone mineral density. Methods According to the current study, the bone mineral density (BMD) and questionnaire survey were performed in 386 Chinese (577 smokers and 229 non-smokers) Han Chinese men in northern China. The main influencing factors were analyzed by stepwise regression analysis. Covariance analysis method to understand the impact of smoking on bone mineral density. Results The BMD of each part decreased with the increase of smoking amount and smoking duration. Daily smoking over 15, lumbar, femoral neck, Ward triangular area and whole body BMD values of 1 12 7,0 95 2,0 844 and 1 148g / cm2, were significantly lower than the daily smoking amount of not more than 15 (1 179,1 0 0 2,0 90 7 and 122 g / cm2). The BMD of femoral neck and Ward triangle were significantly lower than those of non-smokers (0 998 and 0 896 g / cm2, respectively) After confounding factors, this difference is still significant in the lumbar and systemic parts. At the same time smoking more than 15 years, the bone mineral density than the daily amount of less than 15 cigarettes smoked less than 15 years, low 46% to 67%. Conclusions The study initially showed lower bone mineral density in smokers