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目的:分析大剂量奥美拉唑治疗36例老年胃溃疡合并出血的效果。方法:选取72例老年胃溃疡合并出血患者随机分为对照组(36例,常规剂量奥美拉唑治疗)与研究组(36例,大剂量奥美拉唑治疗)。对比不同组别临床指标与临床效果。结果:研究组溃疡愈合时间、止血时间明显短于对照组(P<0.05),抑酸持续时间明显长于对照组(P<0.05),输血量明显少于对照组(P<0.05),血红蛋白水平明显高于对照组(P<0.05),临床总有效率明显高于对照组(P<0.05);两组不良反应出现率差异不明显(P>0.05)。结论:大剂量奥美拉唑治疗老年胃溃疡合并出血能够改善患者临床指标、提升治疗效果,并且不会明显增加不良反应。
Objective: To analyze the effect of high-dose omeprazole in the treatment of 36 elderly patients with gastric ulcer combined with bleeding. Methods: Seventy-two elderly patients with gastric ulcer combined with hemorrhage were randomly divided into control group (36 cases, routine dose of omeprazole treatment) and study group (36 cases, high-dose omeprazole treatment). Comparison of different groups of clinical indicators and clinical effects. Results: The ulcer healing time and bleeding time in the study group were significantly shorter than those in the control group (P <0.05), the duration of acid suppression was significantly longer than that in the control group (P <0.05), blood transfusion volume was significantly less than that in the control group (P <0.05) (P <0.05). The total clinical effective rate was significantly higher than that of the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion: High-dose omeprazole in elderly patients with gastric ulcer combined with bleeding can improve the clinical indicators of patients and improve the therapeutic effect, and will not significantly increase the adverse reactions.