腮腺多形性腺瘤是最常见的涎腺肿瘤,约占所有涎腺肿瘤的60%～70%。该肿瘤以组织病理形态学多样性为特点,主要由包膜、上皮细胞、黏液间质及软骨样组织等成分组成。其标准处理方法是外科手术切除,手术治疗的原则是彻底切除原发部位的病灶。单纯肿瘤剜除术的复发率高达10%～45%,这种高复发率导致手术方式的改变,随着人们对该病的进一步研究认识及对面神经解剖的熟悉,许多学者研究发现包膜的组织病理学特征对多形性腺瘤的复发率有重要影响,剜除术后包膜浸润、伪足、卫星结节等残留导致术后复发。越来越多的学者开始接受腮腺浅叶切除术是腮腺浅叶多形性腺瘤的经典术式,术后的复发率在0.3%～4%。然而有少数学者主张常规行腮腺全切除术。理由是腮腺多形性腺瘤的多中心论。同时有学者研究发现腮腺囊外切除术和区域性切除术复发率与腮腺浅叶切除术相当,术后患者腮腺功能保留并且面貌改变小以及并发症发生率降低。在达到疗效的目的下降低并发症,保留腮腺功能,提高患者生存质量,是医患双方的共同愿望。但该术式的具体切除范围仍不明确。本文对腮腺多形性腺瘤的外科安全手术切缘研究进展予以综述。 Parotid pleomorphic adenoma is the most common salivary gland tumors, accounting for about 60% to 70% of all salivary gland tumors. The tumor is characterized by histopathological morphological diversity and consists mainly of components such as envelope, epithelial cells, mucinous stroma and cartilage-like tissue. The standard method of treatment is surgical resection, the principle of surgical treatment is the complete removal of the lesion of the primary site. The recurrence rate of simple neoplasm resection is as high as 10% -45%. This high recurrence rate leads to the change of operation method. With the further understanding of this disease and the familiarity of facial nerve anatomy, many scholars have found that the Histopathological features of the recurrence rate of pleomorphic adenomas have an important impact, in addition to postoperative envelope infiltration, pseudopodia, satellite nodules and other residues lead to postoperative recurrence. More and more scholars began to accept the parotid shunt resection is a classic parotid pleomorphic adenoma of the classic surgical postoperative recurrence rate of 0.3% to 4%. However, a few scholars advocate routine total parotidectomy. The reason is the polycentricity of parotid pleomorphic adenoma. At the same time, some scholars found that parotid extracapsular resection and regional resection recurrence rate and parotid gland lobectomy surgery is equivalent to postoperative patients with parotid gland function retention and face change small and reduce the incidence of complications. To achieve the purpose of reducing the complications, reserving parotid gland function and improving the quality of life of patients are the common aspiration of both doctors and patients. However, the exact scope of the surgical resection is still not clear. This review summarizes the research progress of surgical margin of surgical safety for parotid pleomorphic adenoma.