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目的探讨医院住院患者HBV感染状况及手术史与HBV感染的关系。方法选择于本院住院患者389例,其中有手术史患者167例,无手术史患者222例。以ELISA方法检测乙肝两对半,将两组出现的11种模式的阳性率进行比较。结果389例住院患者的HBsAg阳性率为13.88%,HBV感染率为58.09%,HBV免疫学指标阴性率41.91%。其中HBsAg、HBeAb、HBcAb阳性者38例(9.76%),HBcAb阳性者25例(6.43%),HBsAg、HBcAb阳性者13例(3.34%)。两组间比较显示,有手术史的患者HBV感染率显著高于无手术史患者(P<0.01)。且两组间,HBsAg、HBeAb、HBcAb阳性模式和HBcAb阳性模式的比较显示有手术史的患者HBV感染阳性率显著高于无手术史患者(P<0.001)。结论住院患者是HBV高感染危险人群。手术是导致医院内HBV感染的方式,需要采取预防措施。
Objective To investigate the relationship between HBV infection and hospitalized patients with HBV infection and surgical history. Methods Select 389 hospitalized patients in our hospital, including 167 patients with history of surgery, 222 patients without history. Two pairs and a half of hepatitis B were detected by ELISA, and the positive rates of 11 patterns in two groups were compared. Results 389 inpatients HBsAg positive rate was 13.88%, HBV infection rate was 58.09%, HBV immunology index negative rate of 41.91%. Of these, 38 (9.76%) were HBsAg, HBeAb and HBcAb positive, 25 (6.43%) were HBcAb positive, and 13 (3.34%) were HBsAg and HBcAb positive. The comparison between the two groups showed that the HBV infection rate of patients with surgery history was significantly higher than that without operation history (P <0.01). Comparisons of HBsAg, HBeAb, HBcAb positive and HBcAb positive between the two groups showed that the positive rate of HBV infection in patients with surgery history was significantly higher than those without operation history (P <0.001). Conclusion Inpatients are at high risk of HBV infection. Surgery is the way to cause HBV infection in the hospital and precautions need to be taken.