1982年,我们开始用正常小鼠肾包膜下移植方法(SRC)测定抗癌药物的敏感性。1986年应用临床治疗女性晚期乳腺癌。本文报告22例,年龄37～60岁,,除2例外,先前曾接受过放疗、化疗。22例中,单药治疗14例,联合用药8例。按国际通用标准评定疗效。结果,单药组及联合用药组的有效率分别为64％和87.5％,明显优于常用有效单药及联合化疗方案。 In 1982, we began measuring the sensitivity of anticancer drugs using the normal mouse subrenal capsule graft method (SRC). Applied clinical treatment of female patients with advanced breast cancer in 1986. This article reports 22 cases, aged 37 to 60 years old, with 2 exceptions, had previously received radiotherapy and chemotherapy. In 22 cases, 14 cases were treated with monotherapy and 8 cases were treated with combination therapy. Efficacy was assessed according to internationally accepted standards. As a result, the effective rates of the single-agent group and the combined-drug group were 64% and 87.5%, respectively, which was significantly better than the commonly available single-agent and combination chemotherapy regimens.