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目的探讨幽门螺杆菌在胃癌前病变中的感染分布及其作用。方法检测内镜及病理确诊的胃癌前病变 43 9例中幽门螺杆菌感染分布情况。结果 43 9例患者中胃癌前病变与性别之间无显著性差别 (P>0 .0 5 )。随着年龄的增长 ,CAG、IM、DYS病变显著增加 ,HP感染率随病变类型的加重而明显上升 ,而且感染的部位逐步上移 (P<0 .0 5 )。结论 HP感染在胃癌前病变发展过程中可能起持续促进作用。常规 HP检测应包括胃窦部及胃体高位
Objective To investigate the distribution of Helicobacter pylori infection in gastric precancerous lesions and its role. Methods The distribution of Helicobacter pylori infection in 439 cases of gastric precancerous lesions confirmed by endoscopy and pathology was examined. Results There was no significant difference between premalignant lesions and gender in 439 patients (P> 0.05). With the increase of age, the incidence of CAG, IM and DYS increased significantly. The infection rate of HP increased significantly with the type of pathological changes, and the infection site gradually increased (P <0.05). Conclusion HP infection may play a continuous role in the development of gastric precancerous lesions. Routine HP testing should include the antrum and upper body