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1984年在武汉市作了胃癌病因学的回顾性病例对照研究。病例来自该市33家医院,1983年1月～1984年10月确诊的病例,149例患者是从中用单纯随机抽样获得。每例按年龄、性别、民族等配以2名近邻健康对照.调查内容有饮食及其习惯、不良嗜好、精神刺激、肿瘤遗传史、血型、文化职业等36个项目。用数量化方法对各项目赋值。用1:2单因分析法筛选出20个影响胃癌发病的因素,又用主成份分析法说明了无相关性较强的因素存在而较适于用条件Logistic多元回归模型作病因学分析。该法选出9个危险因素(RF)和保护因子(PF)。
In 1984, a retrospective case-control study of the etiology of gastric cancer was made in Wuhan. The cases were from 33 hospitals in the city, diagnosed from January 1983 to October 1984, and 149 patients were obtained from random samples. Each case was matched with age, sex, ethnicity, etc. by two neighboring healthy controls. The survey included 36 items including diet and habits, bad habits, mental stimulation, cancer genetic history, blood type, and cultural occupation. Use quantitative methods to assign values to each item. Using the 1:2 single-factor analysis to screen out 20 factors that affect the onset of gastric cancer, the principal component analysis method was used to illustrate the existence of non-correlated factors and was more suitable for the etiological analysis using the conditional Logistic multiple regression model. The law selected nine risk factors (RF) and protective factors (PF).