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目的探讨合并重度肺动脉高压的房间隔缺损(ASD)介入封堵治疗的可行性。方法应用经胸超声心动图(TTE)术中实时监测,对12例合并重度肺动脉高压的ASD进行介入试封堵,其中男性4例,女性8例,年龄46～75岁(56±5岁),比较手术前后右室舒张末期前后径、右心系统血流动力学指标及肺动脉收缩压的变化。结果 12例合并重度肺动脉高压的房间隔缺损均成功封堵,术后右室舒张末期前后径、右心血流动力学指标及肺动脉收缩压均有明显改变(P<0.05)。结论对于合并重度肺动脉高压的继发孔房间隔缺损,应该采取积极的治疗手段。超声心动图贯穿了介入封堵治疗的全过程,为封堵治疗的成功提供了重要的保障。
Objective To investigate the feasibility of atrial septal defect (ASD) complicated with severe pulmonary hypertension. Methods Thoracic echocardiography (TTE) technique was used to monitor the ASD in 12 patients with severe pulmonary hypertension. There were 4 males and 8 females, aged 46-75 years (56 ± 5 years) , Before and after the right ventricular end diastolic anteroposterior diameter, right ventricular hemodynamics and pulmonary artery systolic pressure changes. Results All the 12 cases of atrial septal defect complicated with severe pulmonary hypertension were successfully occluded. The anteroposterior diameter, right ventricular hemodynamics and pulmonary systolic pressure were significantly changed after operation (P <0.05). Conclusion Secondary atrial septal defect with severe pulmonary hypertension should be treated actively. Echocardiography through the whole process of interventional treatment, the success of the closure of the treatment provides an important guarantee.