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治疗原发性血小板减少性紫癜(ITP)的主要手段是皮质醇类激素。脾切除术也可使部分患者改善病情。但仍有30%患者对上述疗法无效,其它替代疗法如:长春新碱、硫唑嘌呤、环磷酰胺、达耶唑,也可使约半数对激素及切脾无效的难治性ITP病人改善病情,但副作用大,疗效不持久,特别是老年性患者死亡率高,本文用干扰素治疗21例难治性ITP患者,报告如下。 病例与方法 21例,男9、女12例。年龄22～70岁,诊断为ITP,经皮质醇激素治疗无效,脾切除
The primary treatment for idiopathic thrombocytopenic purpura (ITP) is cortisol. Splenectomy can also make some patients improve the condition. However, 30% of the patients are still ineffective in the above treatment. Other alternative therapies such as vincristine, azathioprine, cyclophosphamide and darbuzole can also improve about half of refractory ITP patients who have no effect on hormone or spleen spleen Condition, but the side effects, efficacy is not sustained, especially in elderly patients with high mortality, this article with interferon treatment of 21 patients with refractory ITP, the report is as follows. 21 cases and methods, 9 males and 12 females. Aged 22 to 70 years old, diagnosed as ITP, corticosteroid therapy is invalid, splenectomy