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应用单克隆抗体铺皿法分离受60Coγ射线分次照射的小鼠脾脏L3T4、Lyt2和B细胞,测定榄香烯对以上3种亚群细胞和L3T4、Lyt2对B细胞3HTdR掺入的影响;同时测定SOD活力和LPO含量。结果表明:榄香烯提高亚群细胞的辐射抗性,增强了L3T4对B细胞的辅助调节作用,提高脾脏SOD活力和降低LPO含量。
The effect of elemene on the incorporation of 3HTdR into L3 cells and L3T4 cells and Lyt2 cells of B cells were detected by monoclonal antibody-based dish-plating method in spleen L3T4, Lyt2 and B cells of mice irradiated by 60Coγ ray SOD activity and LPO content were determined simultaneously. The results showed that elemene enhanced the radiation resistance of subpopulations, enhanced the regulation of L3T4 on B cells, increased the activity of SOD in the spleen and decreased the content of LPO.