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目的探讨大肠癌微转移ＣＥＡ表达及意义。方法采用免疫组化ＬＳＡＢ法对５４例未发现转移的２８７个淋巴结重新制片，作ＣＥＡ检测及常规染色对比观察。结果８例中１５个淋巴结发现微转移。所有的转移灶免疫组化ＣＥＡ检测均阳性。结论ＣＥＡ检测有助于淋巴结内微转移灶的检出，对Ｄｕｋｅｓ分期、预后的判断及治疗具有重要的意义。
Objective To investigate the expression and significance of CEA in colorectal cancer micrometastasis. METHODS: Fifty-four cases of 287 lymph nodes without metastasis were re-produced using immunohistochemical LSAB method. CEA and conventional staining were compared. Results Micro metastases were found in 15 lymph nodes in 8 cases. All metastases were immunohistochemically positive for CEA. Conclusion The detection of CEA is helpful for the detection of micrometastasis in lymph nodes, and has important significance for the staging and prognosis of Dukes.