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目的 报告 1例分期肝肾联合移植 ,并探讨分期肝肾联合移植治疗技术及其效果。方法 对 1例晚期乙型肝炎肝硬变伴肾功能衰竭患者实施原位肝移植术 ,所用免疫抑制方案为环孢霉素A与甲基强的松龙联合用药 ,于肝移植术后 3个月行肾移植术。结果 肝移植术后肝功能恢复良好 ,但肾功能持续恶化 ,经血液透析治疗无效而行肾移植术。患者肝肾联合移植术后 9个月 ,一般情况良好 ,移植肝和移植肾功能均正常。结论 对肝移植后各种原因导致的肾功能衰竭 ,当血液透析治疗无效时可再行肾移植术。同时 ,免疫抑制剂用量并未增加。
Objective To report a case of liver-kidney transplantation combined with staging and discuss the staging of liver-kidney transplantation and its effects. Methods One patient with advanced hepatitis B cirrhosis and renal failure underwent orthotopic liver transplantation. The immunosuppressive regimen used was combination of cyclosporine A and methylprednisolone, and after three liver transplantation Month line kidney transplantation. Results Liver function recovered well after liver transplantation, but renal function continued to deteriorate. Renal transplantation was ineffective after hemodialysis. Patients with liver and kidney transplantation 9 months after transplantation, the general situation is good, liver graft and kidney function are normal. Conclusion Renal failure due to various causes after liver transplantation can be performed again when hemodialysis is ineffective. At the same time, the amount of immunosuppressive agents did not increase.