神经生长因子 (ＮＧＦ)在外周及中枢神经系统的发育及存活方面起着重要的作用。它可以促进外周感觉神经元及背根神经节神经元的增生。中枢神经系统中 ,ＮＧＦ主要存在于前脑底部胆碱神经元中 ,其脑中含量的减少与Ａｌｚｈｅｉｍｅｒ病引起的记忆力减退及老年斑沉积呈正相关[1] Nerve growth factor (NGF) plays an important role in the development and survival of the peripheral and central nervous system. It promotes the proliferation of peripheral sensory and dorsal root ganglion neurons. In the central nervous system, NGF is mainly present in the cholinergic neurons at the base of the basal forebrain, and its decrease in brain content is positively correlated with memory loss and senile plaque deposition caused by Alzheimer’s disease [1]