论文部分内容阅读
目的应用双源CT(DSCT)冠状动脉血管造影探讨2型糖尿病患者冠状动脉病变(CAD)的特点。方法收集2010年12月-2012年11月行冠状动脉双源CT造影的患者资料。对符合标准的302例患者(2型糖尿病74例,非糖尿病228例)进行冠状动脉CT血管造影检查。观察所有图像,评价CAD的斑块类型以及引起病变血管的狭窄程度。结果与非糖尿病患者相比,2型糖尿病患者冠状动脉斑块数目较多,差异有统计学意义(P<0.01),尤其是混合斑块与非钙化斑块(P<0.01);2型糖尿病患者钙化斑块、混合斑块、非钙化斑块构成比分别为29.1%、41.1%、29.8%,非糖尿病组患者分别为39.7%、36.0%、24.3%,两组构成差异有统计学意义(P<0.05);2型糖尿病患者冠状动脉血管发生轻、中、重度狭窄的病变数目较非糖尿病患者多,且两组之间差异均有统计学意义(P<0.05)。结论 2型糖尿病CAD患者有较高的斑块负荷(混合斑块最常见),且容易引起管腔狭窄。
Objective To investigate the characteristics of coronary artery lesions (CAD) in patients with type 2 diabetes by dual-source computed tomography (DSCT) coronary angiography. Methods The data of patients undergoing double-source CT coronary angiography from December 2010 to November 2012 were collected. Coronary CT angiography was performed on 302 eligible patients (74 type 2 and 228 non-diabetic). All images were observed, the plaque type of CAD was evaluated, and the degree of stenosis of the diseased vessels was evaluated. Results Compared with non-diabetic patients, the number of coronary plaques in type 2 diabetic patients was significantly higher than that in non-diabetic patients (P <0.01), especially in mixed plaques and non-calcified plaques (P <0.01) The proportions of calcified plaque, mixed plaque and non-calcified plaque were 29.1%, 41.1% and 29.8% in non-diabetic patients and 39.7%, 36.0% and 24.3% in non-diabetic patients, respectively. There was significant difference between the two groups P <0.05). The number of mild, moderate and severe coronary lesions in patients with type 2 diabetes was more than that in non-diabetic patients, and there was significant difference between the two groups (P <0.05). Conclusions CAD patients with type 2 diabetes mellitus have a higher plaque load (mixed plaque is the most common) and tend to cause lumen stenosis.