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目前认为,退行性中心性脉络膜视网膜营养不良(UXP)是一种多病原学疾病。一些作者指出,在眼底营养不良的发展过程中,脉络膜血管床微循环发生障碍是一个重要因素。Bonnet(1984)提出了静脉破坏术——外侧涡状静脉破坏术,以增加红细胞和脉络膜毛细血管壁内皮的接触时间,改善视网膜的微循环。血液流变学,特别是红细胞聚集性和血液粘性对脉络膜与视网膜毛细血管中的代谢产生影响,口前尚缺乏UXP 患者血液流变学及凝血系统方面资料。故观察这些变化对其发病学的研究和治疗方法的选择具有重要意义。为此,测定UXP 患者周围围中液变学和凝血指标;测定UXP 患者涡状静脉中某些血液流变学和凝血指标;根据上述各项指标顶测静脉破坏术的效果。选择34例(男15女19)年龄在50～80岁(平均
It is currently believed that degenerative central chorioretinal dystrophy (UXP) is a polypathogenic disease. Some authors pointed out that in the development of fundus malnutrition, choroidal vascular bed microcirculation disorder is an important factor. Bonnet (1984) proposed a venous thrombo-lateral vortex venous destruction in order to increase the contact time of erythrocytes with the endothelium of the choriocapillaris wall and improve the microcirculation of the retina. Hemorheology, especially erythrocyte aggregation and blood viscosity, affects the metabolism of the choroid and the retinal capillaries. Hematological and coagulopathic data on UXP patients are lacking. Therefore, it is of great significance to observe these changes on the study of their pathogenesis and treatment options. To this end, we measured perinatal fluid changes and coagulation markers in UXP patients; measured some hemorheology and coagulation indices in the vortex veins of UXP patients; and determined the effects of venous thromboembolism according to the above indexes. Choose 34 cases (15 boys and 19 girls) aged 50 to 80 years (mean