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目的 :探讨精浆中微量元素与血清生殖激素的关系。方法 :采用原子吸收分光光度法和放免法 ,测定17例不育和 2 1例已育男子精浆及血清中锌、铜、铁、锰、镍和生殖激素水平。结果 :不育组血清锌明显降低 ,而黄体生成素和泌乳素高于对照组 (均P <0 0 5 ) ;对照组精浆锌与雌二醇、铜与睾酮呈正相关 (分别为P <0 0 1,P <0 0 5 ) ;不育组精浆铁与黄体生成素负相关 (P <0 0 1) ,与泌乳素及睾酮呈正相关 (P <0 0 5 )。结论 :评估男性生育力需协同分析精浆微量元素和血清生殖激素水平
Objective: To explore the relationship between trace elements in serum and serum reproductive hormones. Methods: The levels of zinc, copper, iron, manganese, nickel and reproductive hormones in 17 infertile and 21 semen of infertile men and serum were determined by atomic absorption spectrophotometry and radioimmunoassay. Results: Serum zinc was significantly decreased in the infertility group, while that of luteinizing hormone and prolactin was higher than those in the control group (all P <0.05). There was a positive correlation between zinc and estradiol and copper and testosterone in the control group (P < 0 0 1, P <0 05). There was a negative correlation between iron and serum luteinizing hormone in sterility group (P <0.01), and a positive correlation with prolactin and testosterone (P <0.05). CONCLUSIONS: The assessment of male fertility requires a synergistic analysis of serum and trace elements and serum reproductive hormones