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目的观察睡眠呼吸暂停对接受冠状动脉支架植入后再狭窄的的影响。方法选择54例急性冠状动脉综合征患者为观察组,所有患者利用冠状动脉支架植入术进行治疗,另选54例为对照组,进行冠状动脉造影。结果观察组最低氧饱和度、暂停低通气指数、最长呼吸暂停时间等指标明显长于对照组;观察组晚期管腔丢失与对照组相比有明显增高趋势;观察组C-反应白丹、纤维蛋白原明显高于对照组;观察组新发病变略高于对照组。结论睡眠呼吸暂停患者经冠状动脉支架植入术后晚期管腔丢失存在增高的趋势,可见冠脉支架术后再狭窄的发生可能和睡眠呼吸暂停相关。
Objective To observe the effect of sleep apnea on restenosis after coronary stent implantation. Methods 54 patients with acute coronary syndrome were selected as observation group. All patients were treated by coronary stent implantation. Another 54 patients were selected as control group for coronary angiography. Results The lowest oxygen saturation, the index of hypopnea, the longest apnea time in the observation group were significantly longer than those in the control group. The late luminal loss in the observation group was significantly higher than that in the control group. The C-reactive bletilla, fiber Prokaryotic protein was significantly higher than the control group; observation group new onset slightly higher than the control group. Conclusions There is an increasing tendency of late luminal loss in patients with sleep apnea after coronary stenting. It is concluded that restenosis after coronary stenting may be related to sleep apnea.