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自1948年柯萨奇病毒(C病毒)首次被分离后,B组C病毒被认为是引起新生儿严重疾病的病原。临床表现经常与细菌性脓毒症相类似,并常伴有多脏器受累,如脑膜脑炎、心肌炎、肺炎、肝炎及血小板减少等。本例为新生儿C病毒B-4感染、有脑炎、心肌炎、并有心肌钙化及左束枝传导阻滞等少见的并发症。病例报告:病儿男性、生于1978年9月27日,初生重2,500g。其母25岁,于产前2天曾有高热(40℃)及腹痛。婴儿生后给氧24小时,但其他情况尚好。第3天出现发热、第8天表现昏睡,发绀及中度呼吸困难。体温37.8℃,脉搏150次/分,呼吸80次/分,肝肋下3cm,脾肋下1cm,其他体征无明显阳性所见。
Group B C-virus is thought to be the causative agent of serious illness in the newborn since Coxsackievirus (C) was first isolated in 1948. Clinical manifestations often resemble bacterial sepsis and are often associated with multiple organ involvement such as meningoencephalitis, myocarditis, pneumonia, hepatitis, and thrombocytopenia. This case of neonatal C virus B-4 infection, encephalitis, myocarditis, and myocardial calcification and left bundle branch block and other rare complications. Case report: sick child male, born in September 27, 1978, birth weight 2,500g. The mother is 25 years old and had high fever (40 ° C) and abdominal pain 2 days before delivery. Oxygen for 24 hours after birth, but other conditions are good. Fever on day 3, lethargy on day 8, cyanosis and moderate dyspnea. Body temperature 37.8 ℃, pulse 150 beats / min, breathing 80 beats / min, liver ribs 3cm, 1cm under the splenic ribs, other signs no significant positive seen.