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目的 通过被覆支架治疗晚期食管癌恶性狭窄 ,并行术后放射治疗 ,以提高生活质量 ,延长生存期。方法 晚期食管癌恶性食管狭窄 18例 ,狭窄直径均在 2 .5mm以下 ,其中 3例呈梗阻状 ,4例合并有食管瘘 ,1例出现肝部转移。经口置入镍钛合金被覆支架 2 0枚 ,于 2周后行外照射 ,肿瘤试剂照射剂量 (DT) :6 0～ 70Gy。结果 所有患者均一次顺利完成支架置入 ,患者进普食顺利 ,疗效满意。 2周后均顺利接受放射治疗 ,未出现并发症。经随访复查 ,支架未发生移位及出现再狭窄改变 ,食管通畅 ,患者进食顺利 ,生存期延长 ,平均 11个月。结论 被覆支架治疗晚期食管癌恶性食管狭窄及术后结合放疗 ,能有效地抑制肿瘤生长 ,提高生活质量 ,延长生存期 ,是治疗晚期食管癌患者的一种安全有效的治疗方法。
Objective To treat malignant stenosis of advanced esophageal cancer by stent-graft and perform postoperative radiotherapy in order to improve the quality of life and extend the survival period. Methods 18 patients with advanced esophageal malignant esophageal stenosis, stenosis diameter were 2.5mm or less, of which 3 were obstructive, 4 patients with esophageal fistula, 1 case of liver metastasis. Orthopedic NiTi alloy stent 20, 2 weeks after the external irradiation, tumor agent irradiation dose (DT): 60 ~ 70Gy. Results All patients were successfully stent placement, the patient into the general diet smoothly, the effect is satisfactory. Radiotherapy was successfully received after 2 weeks without complications. After follow-up review, the stent did not shift and restenosis, esophageal patency, patients eat smoothly, prolong survival, an average of 11 months. Conclusion The stent-graft treatment of advanced esophageal malignant esophageal stenosis and postoperative combined with radiotherapy can effectively inhibit tumor growth, improve quality of life and prolong survival. It is a safe and effective treatment for patients with advanced esophageal cancer.