液体石蜡乳的配制

来源 :中国药学杂志 | 被引量 : 0次 | 上传用户:drink_xo
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在改善药剂色香味的措施中,我们将液体石蜡制成水包油型的乳剂供内服用。乳化后的液体石蜡,尤其是添加了色香味后,较之原来单纯的液体石蜡大为适口。采用阿刺伯树胶与琼脂为乳化剂所做成的液体石蜡,一般内含主药50%,当有足量琼脂存在时(10%以上),产品呈半固体的冻膏状,稳定度高,不易分层。琼脂用量的降低,或单用阿刺伯树胶所制得的液体石蜡乳剂,虽亦稳定,却很容易发生分层,放置短时间即便呈现。琼脂价较高昂,增加琼蜡的用量,势必增加药品的价格,而且使用琼脂制造乳剂,必须加热使溶化,搅拌至冷冻,费时既久,手续亦烦。鉴于这些原因,同时根据实验的比较,我院系用镁乳与阿刺伯树胶 In the measure to improve the color and fragrance of the medicament, we made the liquid paraffin as an oil-in-water emulsion for oral administration. Emulsified liquid paraffin, especially after the addition of color and fragrance, is more palatable than the original liquid paraffin. Using acanthopanax sesame and agar as emulsifier made of liquid paraffin, usually containing 50% of the main drug, when sufficient agar (10% or more), the product was semi-solid frozen paste, high stability , Not easy to stratification. The amount of agar decreased, or Acacia alone obtained liquid paraffin emulsion, although also stable, but it is easy to stratification, even for a short period of time present. Agar is more expensive, increasing the amount of Jojoba wax is bound to increase the price of drugs, and the use of agar to make emulsions, must be heated to dissolve, stir to freeze, take a long time, the procedures annoying. For these reasons, at the same time based on the experimental comparison, my department with magnesium milk and acacia gum
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