用细胞培养法和癌细胞侵袭实验，观察几种植物来源不同作用机理的抗癌药如紫杉醇、三尖杉酯碱、高三尖杉酯碱及喜树碱［１］，对黑色素瘤高转移株Ｂ１６ＢＬ６细胞及人纤维肉瘤细胞ＨＴ１０８０的细胞毒作用和抗侵袭作用。结果表明紫杉醇、三尖杉酯碱、高三尖杉酯碱及喜树碱对Ｂ１６ＢＬ６和ＨＴ１０８０细胞增殖均有很强的抑制作用。紫杉醇、三尖杉酯碱及高三尖杉酯碱对Ｂ１６ＢＬ６细胞侵袭和运动也有明显的抑制作用，而喜树碱在同样浓度下对Ｂ１６ＢＬ６细胞侵袭和运动均无明显抑制。 Cell culture and cancer cell invasion experiments were performed to observe several cancer-fighting agents with different mechanisms of action from plant sources such as paclitaxel, harringtonine, homoharringtonine and camptothecin [1] B16  BL6 cells and human fibrosarcoma cells HT  1080 cytotoxicity and anti-invasive effect. The results show that paclitaxel, harringtonine, homoharringtonine and camptothecin on B16  BL6 and HT  1080 cells have a strong inhibitory effect on proliferation. Paclitaxel, harringtonine and homoharringtonine B16 BL6 cell invasion and exercise also significantly inhibited the role of camptothecin in the same concentration of B16 BL6 cell invasion and exercise were not significantly inhibited.