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一例辐射事故病人外周血淋巴细胞HPRT基因突变谱分析赵艳华邢瑞云夏寿萱次黄嘌呤磷酸核糖转移酶(HPRT)基因是研究电离辐射所致DNA损伤和衡量对人体的近、远期辐射效应较为理想的靶基因。作者利用计算机辅助设计,合成HPRT基因全部外显子的寡核苷酸引物,...
A case of radiation accident HPRT gene mutation in peripheral blood lymphocytes Zhao Yanhua Xing Ruiyun Xia Shousuan hypoxanthine phosphoribosyltransferase (HPRT) gene is to study DNA damage induced by ionizing radiation and to measure the human body near and long-term radiation effect of the ideal target gene. Using computer-aided design, the authors synthesized oligonucleotide primers for all exons of the HPRT gene, ...