用立体学测量技术研究了5例小儿亚急型克山病心肌的超微结构。研究结果是,亚急型克山病单位容积肌细胞中线粒体容积明显增大;单位容积肌细胞中肌原纤维容积明显减少;线粒体与肌原纤维的容积比例增大;线粒体断面的平均面积增大。这些结果首次从定量方面证明了克山病心肌的定性电镜观察,为分析本病的发病机理提供定量形态学资料。 The ultrastructure of myocardium in children with subacute Keshan disease was studied by stereological measurement technique. The result of the study was that the volume of mitochondria in unit-size myocytes of subemeral Keshan disease was significantly increased, the volume of myofibrils in unit volume of muscle cells was significantly reduced, the volume ratio of mitochondria and myofibrils was increased, and the average area of ​​mitochondrial cross sections increased. Big. These results demonstrate for the first time qualitative qualitative electron microscopic observation of Keshan disease myocardium and provide quantitative morphological data for analyzing the pathogenesis of this disease.