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目的观察卡托普利联合黄芪注射液治疗病毒性心肌炎的效果。方法选取三门峡市中医院2014年3月—2015年8月收治的病毒性心肌炎患者102例,根据平行、单盲、随机对照的设计原则分为对照组(n=50)和观察组(n=52)。对照组患者接受常规治疗,观察组在对照组基础上采用卡托普利联合黄芪注射液治疗,比较两组患者的治疗效果、心功能情况及不良反应发生情况。结果观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组患者左室射血分数高于对照组,乳酸脱氢酶、天冬氨酸氨基转移酶、肌酸激酶同工酶水平低于对照组,差异有统计学意义(P<0.05)。两组患者均未出现严重不良反应。结论卡托普利联合黄芪注射液治疗病毒性心肌炎效果明显,且能够显著改善患者心功能,安全性好。
Objective To observe the effect of captopril combined with astragalus injection in the treatment of viral myocarditis. Methods Totally 102 patients with viral myocarditis admitted to Sanmenxia Hospital of Traditional Chinese Medicine from March 2014 to August 2015 were divided into control group (n = 50) and observation group (n = 50) according to the design principles of parallel, single blind and randomized control 52). Patients in the control group received routine treatment. The observation group was treated with captopril combined with Astragalus injection on the basis of the control group. The therapeutic effect, cardiac function and adverse reactions of the two groups were compared. Results The total effective rate of observation group was higher than that of control group (P <0.05). The left ventricular ejection fraction of observation group was higher than that of control group, and lactate dehydrogenase, aspartate aminotransferase, The level of acid kinase isozyme was lower than that of the control group (P <0.05). No serious adverse reactions occurred in both groups. Conclusion Captopril combined with astragalus injection in the treatment of viral myocarditis obvious effect, and can significantly improve the patient’s cardiac function, good safety.