论文部分内容阅读
腺苷(内源性嘌呤核苷)是一种有效的抗心律失常药,可延缓房室结的传导而终止包括房室结折返性室上性心动过速(SVT)。多数儿童的SVT是由于房室折返所致,且常常存在旁道,故腺苷治疗应当是有效的。病例及方法受试者为反复发作的SVT患儿,经其它药物治疗均无效。其中3例为病情严重的新生儿,因长时间自发性SVT而有心衰,另1例10岁为进行选择性电生理学研究而入院。亲属中有哮喘史(腺苷吸入时有轻度支气管收缩作用,静注无此作用)同时用潘生丁(可增强静脉内外源性腺苷作用)治疗
Adenosine (an endogenous purine nucleoside) is a potent antiarrhythmic drug that delays the conduction of the AV node and terminates, including atrioventricular nodal reentrant supraventricular tachycardia (SVT). The majority of children with SVT are due to atrioventricular reversion, and there are often bypasses, so adenosine therapy should be effective. Patients and Methods Subjects with recurrent SVT were ineffective with other medications. Three of them were newly diagnosed children with heart failure due to long-term spontaneous SVT. The other 10-year-old was admitted for selective electrophysiological studies. Relatives have a history of asthma (adenosine inhalation mild bronchoconstriction, intravenous no such effect) while dipyridamole (can enhance the role of intravenous exogenous adenosine treatment)