一、概述在胚胎期或新生儿期发现的大多数肾脏疾病,多为先天畸形和遗传性疾病。畸形通常散发,往往很难解释其发病机制。而遗传性疾病通常有较明显的染色体显性或隐形遗传形式,大部分异常基因位点及相关蛋白已经明确,见表1。重症先天性肾脏 First, an overview of most of the kidney disease found in the embryonic or neonatal period, mostly congenital malformations and genetic diseases. Deformity is usually distributed, it is often difficult to explain the pathogenesis. Hereditary diseases usually have more obvious dominant or invisible genetic forms of chromosomes, most of the abnormal gene loci and related proteins have been identified (Table 1). Severe congenital kidney