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目的 寻找强身丹的最佳组方方案 ,确定其中药物配伍的主次和适宜的剂量水平。方法 采用正交设计L16(43 × 2 6) ,以老年小白鼠肝组织SOD活力和LPO含量为观察指标。结果 强身丹组方药物从 9味精简到 4味药 ,并确定了 4味药物配伍的适宜剂量和主次地位。结论 证实了传统中医防老抗衰方剂组方模式的合理性和科学性 ,为创制延缓衰老新的方剂提供了思路。
Objective To search for the best formulation of Qiandandan to determine the primary and secondary levels of the drug and the appropriate dose level. Methods Orthogonal design L16 (43 × 26) was used to observe SOD activity and LPO content in liver tissue of aged mice. Results The results showed that the drug for the body of Danzengdan was reduced from 9 to 4 herbs, and the appropriate dose and priority of the compatibility of 4 herbs were determined. Conclusions The rationality and scientificity of the traditional Chinese medicine anti-aging and anti-aging prescriptions are proven, which provides ideas for creating new prescriptions for delaying aging.