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目的 :观察汉防己甲素 (Tetrandrine ,Tet)对实验性急性胰腺炎 (AP)的治疗效果 ,并对其作用机制进行探讨。方法 :取 1 76只SD大鼠 ,雌雄不拘 ,随机分为Tet组、维拉帕米组等 6组 ,经胰胆管逆行注射 3%牛磺脱氧胆酸钠 0 .1mL/1 0 0g体重 ,制成急性胰腺炎
Objective: To observe the therapeutic effect of tetrandrine (Tet) on experimental acute pancreatitis (AP) and to explore its mechanism. Methods: One hundred and seventy-six SD rats were randomly divided into Tet group and verapamil group. The rats were retrogradely injected with 0.1% sodium taurodeoxycholate 0,1 g / 100 g body weight through pancreaticobiliary duct, Made of acute pancreatitis