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作者报道一例感染后27天的侵袭期曼氏血吸虫病用吡喹酮治疗失败的经验教训。患者男性,法国人,33岁,出生于巴黎,1983年5月10日至26日曾居留于中非共和国,并在5月15日因在疫区游泳而感染曼氏血吸虫。回巴黎后不久即因出现不规则高热(40℃)、寒战、头痛、明显乏力及轻度肌痛等征象,而于同年6月4日入院。入院时检查心、肺、神经系统、皮肤、淋巴腺及肝脾均无异常,血吸虫病血清学试验阴性,血、粪培养阴
The authors report on a case of failure of praziquantel treatment of schistosoma mansoni at 27 days after infection. Patient Male, French, 33 years old, born in Paris and resident in the Central African Republic from 10 to 26 May 1983 and infected with Schistosoma mansoni on 15 May due to swimming in the affected area. Not long after returning to Paris, he was admitted to hospital on June 4 of the same year because of signs of irregular high fever (40 ° C), chills, headache, marked weakness and mild myalgia. Admission examination heart, lung, nervous system, skin, lymph nodes and liver and spleen were normal, schistosomiasis serological test negative, blood, fecal culture yin