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目的提取并筛选具有抑杀蠕形螨作用的中药材挥发油。方法采用透明胶带粘贴法获取蠕形螨,镜下观察不同中药材挥发油对蠕形螨的抑杀作用,并设立新肤螨灵软膏为阳性对照,生理盐水为阴性对照,进行体外抗螨活性筛选。结果良姜、枳壳、细辛、桂皮、丁香、花椒6种中药材挥发油具有较好的抑杀蠕形螨效果,对2种蠕形螨均有明显的抑杀作用,其中丁香、细辛2种中药材挥发油对毛囊蠕形螨的抑杀效果优于皮脂蠕形螨。结论丁香、枳壳等6种中药材挥发油具有良好的体外抑杀蠕形螨活性。
Objective To extract and screen the essential oils of Chinese medicinal materials with the effect of killing demodex. Methods The demodex was used to obtain demodex by transparent tape, and the killing effect of volatile oils of different Chinese herbs on Demodex was observed under microscope. The Xinfufuling ointment was established as a positive control, and saline was a negative control. . Results The volatile oils of six kinds of Chinese medicinal materials, including galangal, oyster shell, asarum, cinnamon, clove, and pepper, had good killing and demodex effects, and they had significant killing effects on the two demodex, including clove and asarum. The killing effect of two kinds of Chinese herbal volatile oil on Demodex folliculorum was superior to that of sebaceous demodex. Conclusion The volatile oils of 6 kinds of Chinese herbal medicines, such as clove and oyster shell, have a good activity of killing Demodex in vitro.