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目的比较长期服药治疗的患者自述用药依从性与医生评估的用药重要性之间的差异。方法本研究选取的患者在法国医院内及医院外接受了至少1个周期的长期药物治疗。使用开放式问卷调查患者用药非依从性的原因,并将其分为有意或无意两类。采用Spearman相关系数就患者与医生对用药依从性及其重要性的评价数据进行比较分析。结果 2014年4—8月选取服用498种药物的128例患者。患者和医生在对用药依从性及其重要性的评价上表现出很大分歧〔r=-0.25,95%CI(-0.37,-0.11);r=0.07,95%CI(0,0.13)〕。医生评价的用药重要性与患者自述的用药依从性之间没有任何关联〔r=-0.04,95%CI(-0.14,0.06)〕。共有94种(18.9%)医生认为重要的药物而患者没有认真遵循医嘱服用。患者有意没有坚持服用的药物有26种(48.1%)。结论患者与医生对用药依从性及其重要性评价之间存在很大的差异;约有20%的医生认为重要的药物,患者没有认真遵循医嘱服用,这些情况表明医生与患者在药物治疗方面需要更好地协作。
OBJECTIVE: To compare the discrepancies between self-reported adherence and the importance of physician-assessed medication in patients treated with long-term medication. Methods Patients selected in this study received at least 1 cycle of long-term medication in and outside the French hospital. An open questionnaire was used to investigate the reasons for the non-adherence of patients to medication and divided into two categories, intentionally or unintentionally. Spearman’s correlation coefficient was used to compare the evaluation data of patients ’and doctors’ compliance with medication and its importance. Results From April to August 2014, 128 patients taking 498 drugs were selected. Patients and physicians have shown considerable divergences in the evaluation of drug adherence and its importance [r = -0.25, 95% CI (-0.37, -0.11); r = 0.07, 95% CI . There was no association between the importance of medication as evaluated by the physician and patient compliance (r = -0.04, 95% CI (-0.14, 0.06)). A total of 94 (18.9%) of the medications were considered important by the patient and the patient did not follow the doctor’s instructions carefully. Twenty-six species (48.1%) of patients deliberately did not insist on taking the drug. Conclusion There is a big difference between patients ’and doctors’ evaluation of drug compliance and its importance. About 20% of doctors think that important drugs are not conscientiously taken by doctors. These conditions indicate that doctors and patients need medical treatment Better collaboration.