一个世纪前就已知自身免疫性疾病可影响循环血中的终末期细胞。近些年来还了解到自身免疫性溶血性贫血全再障型和选择性红细胞再障型的免疫介导损害可累及骨髓。原发性或继发性粒细胞缺乏症骨髓中性粒细胞的消失就是一种骨髓受累的典型,常伴有粒系祖细胞增生高峰的出现。这些患者骨髓中的祖细胞象外周血的终末细胞一样,在相同的疾病过程和免疫损害中也受到波及。周围型自身免疫性疾病中,骨髓巨噬细胞象肝、脾的一样活跃,这是全身性免疫介导扣押过程的局部表现。最近已知一种或多种循环 A century ago it was known that autoimmune diseases affect end-stage cells in circulating blood. It has also been recognized in recent years that immune-mediated damage to autoimmune hemolytic anemia full-reticulosis and selective erythrocyteritation syndrome can affect bone marrow. Primary or secondary agranulocytosis The disappearance of myeloid neutrophils is a classic example of bone marrow involvement, often accompanied by the appearance of proliferative granulocyte progenitors. The progenitor cells in the bone marrow of these patients, like the terminal cells of peripheral blood, are also affected by the same disease processes and immune damage. In peripheral autoimmune diseases, bone marrow macrophages are as active as the liver and spleen, which is a local manifestation of the systemic immune-mediated seizure process. One or more cycles have recently been known