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目的:探讨小儿顽固性肺炎的体液免疫状态并对其行免疫调节治疗。方法:对34例顽固性肺炎进行血清丙种球蛋白、免疫球蛋白及补体C3的测定,并予相应的丙种球蛋白替补疗法。结果:所有顽固性肺炎病例体液免疫均有异常,而且以丙种球蛋白的降低显著,其中23例行免疫调节治疗,疗效满意。结论:早期着眼于免疫调节是防治小儿顽固性肺炎体液免疫缺陷的重要环节。
Objective: To investigate the status of humoral immunity in children with intractable pneumonia and immunomodulatory therapy. Methods: 34 cases of refractory pneumonia serum gamma globulin, immunoglobulin and complement C3 determination, and to the corresponding gamma globulin replacement therapy. Results: All cases of intractable pneumonia were abnormal humoral immunity, and to reduce significantly gamma globulin, of which 23 cases of immunomodulatory therapy, with satisfactory results. Conclusion: Early attention to immune regulation is an important part of the prevention and treatment of refractory childhood humoral immune deficiency.